Restylane Defyne, along with its’ counterpart Restylane Refyne, are the newest additions to the Restylane family of dermal fillers. Brought to us by Galderma, the makers of Dysport, Restylane Defyne is a hyaluronic acid filler that replenishes lost facial volume related to age, weight loss, and other causes.

Restylane Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). Using innovative cross-linking technology, Restylane Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.

Restylane Defyne is used to:

  • Fill in nasolabial folds, the lines that run from the corners of the nose to the corners of the mouth
  • Smooth marionette lines, the wrinkles that form between the corners of the mouth and the chin and jawline
  • Address mild-to-moderate wrinkles and folds
  • Provide facial rejuvenation in the lower face, around the mouth

How is the Restylane Defyne procedure performed?

Topical numbing or ice may be used, but isn’t necessary as the injectable filler contains lidocaine, a local anesthetic. Dr. Sobel will perform a series of injections using a fine-gauge needle into the treatment area. They will then mold and shape the filler for best results. Once injections begin, your Defyne treatment can take anywhere from 15-30 minutes. After treatment, ice can be applied to help with swelling.

Are Restylane Defyne injections painful?

Lidocaine, an injectable local anesthetic, is included in each syringe of Defyne. This helps ensure patient comfort during the procedure. Most patients report only a slight pinching or poking sensation and rate the procedure as very comfortable. If you are concerned about discomfort during treatment, you may opt to receive a topical numbing cream and/or ice.

How long will the results of a Restylane Defyne treatment last?

No two patients are alike, and everyone metabolizes injectables differently. However, during clinical trials, the results of Restylane Defyne lasted up to 12 months in over 65% of patients. Over 70% of patients continued to see results after 6 months.