Restylane® Defyne, along with its’ counterpart Restylane® Refyne, are the newest additions to the Restylane® family of dermal fillers. Brought to us by Galderma, the makers of Dysport®, Restylane® Defyne is a hyaluronic acid filler that replenishes lost facial volume related to age, weight loss, and other causes.

Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). Using innovative cross-linking technology, Restylane® Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.

Restylane® Defyne is used to:

  • Fill in nasolabial folds, the lines that run from the corners of the nose to the corners of the mouth
  • Smooth marionette lines, the wrinkles that form between the corners of the mouth and the chin and jawline
  • Address mild-to-moderate wrinkles and folds
  • Provide facial rejuvenation in the lower face, around the mouth

How is the Restylane® Defyne procedure performed?

Topical numbing or ice may be used, but isn’t necessary as the injectable filler contains lidocaine, a local anesthetic. Dr. Sobel will perform a series of injections using a fine-gauge needle into the treatment area. They will then mold and shape the filler for best results. Once injections begin, your Defyne treatment can take anywhere from 15-30 minutes. After treatment, ice can be applied to help with swelling.

Are Restylane® Defyne injections painful?

Lidocaine, an injectable local anesthetic, is included in each syringe of Defyne. This helps ensure patient comfort during the procedure. Most patients report only a slight pinching or poking sensation and rate the procedure as very comfortable. If you are concerned about discomfort during treatment, you may opt to receive a topical numbing cream and/or ice.

How long will the results of a Restylane® Defyne treatment last?

No two patients are alike, and everyone metabolizes injectables differently. However, during clinical trials, the results of Restylane® Defyne lasted up to 12 months in over 65% of patients. Over 70% of patients continued to see results after 6 months.